Familial cavernous angiomas masquerading as multiple sclerosis.
نویسندگان
چکیده
We report here two cases of cavernous angioma, in the proband and her father, with quite different clinical presentations. The proband presented with a brainstem syndrome, mimicking multiple sclerosis, while the father had a history of mild epilepsy. Both patients were managed conservatively. The cases also demonstrate the utility of magnetic resonance imaging in the diagnosis of cavernous angioma.
منابع مشابه
Congenital multiple cavernous angiomas associated with thrombosed arteriovenous malformation of the brain--case report.
A 16-year-old girl presented with multiple cerebral cavernous angiomas with calcifications due to repeated hemorrhages and a thrombosed cerebral arteriovenous malformation (AVM). Her 18-year-old elder sister also had multiple cerebral cavernous angiomas associated with calcifications, which suggested presence of repeated previous hemorrhages. Surgical removal via a right occipital craniotomy re...
متن کاملClinical progression and familial occurrence of cerebral cavernous angiomas: the role of angiogenic and growth factors.
OBJECT The authors studied the expression of angiogenic and growth factors and various proliferative indices in cavernous angiomas of the brain. The goal was to define whether the often progressive clinical course of both sporadic and familial forms of the lesion is correlated with different expression of these factors. METHODS Forty-three cavernomas of the brain were investigated with immuno...
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Cerebral cavemous angiomas are rare lesions; they constitute 3% to 13% of intraaanial vascular malformations (6).Cavemous angiomas may affect any part of the central nervous system and usually present with seizures. focal signs or haemorrhage (1.8). These lesions may bleed. calcify or thrombose (8).A1though they may involve any part of the central nervous system. lesions located in brain stern ...
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Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue. We report 2 cases of familial CCMs diagnosed with the CCM1 mutation by using a genetic assay. A 5-year-old boy presented with headache, vomiting, and seizure-like movements. Brain magnetic resonance imaging (MRI) revealed multiple CCM le...
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عنوان ژورنال:
- Postgraduate medical journal
دوره 74 874 شماره
صفحات -
تاریخ انتشار 1998